Research Article

Transcriptional Profiling Suggests Extensive Metabolic Rewiring of Human and Mouse Macrophages during Early Interferon Alpha Responses

Figure 7

Expression of genes associated with lipid metabolism were differentially modulated in IFN-α-stimulated BMM compared MDM. Differentially expressed metabolic genes (, , ) involved in cholesterol metabolism and phospholipid and sphingolipid synthesis were mapped using MetScape and DAVID. Green and red represent genes that have been significantly upregulated or downregulated, respectively. Blue represents genes that were not altered following IFN-α stimulation.