The Transient Receptor Potential Vanilloid 1 Is Associated with Active Inflammation in Ulcerative Colitis

Figure 1

Gene expression of TRPV1 and IL-6 quantified by RT-PCR in colonic mucosa from patients with active and remission UC compared to non-IBD controls. (a) TRPV1 mRNA expression levels. (b) IL-6 mRNA expression levels. Bars show mean ± standard error of the mean of transcript levels from UC patients with β-actin as housekeeping gene determined by 2^−∆∆Ct. value < 0.05 was considered as significant. Panels (c), (d), and (e) showed original RT-PCR cycles to clearly appreciate the level of TRPV1 mRNA expression in active UC, normal controls, and remission UC, respectively.

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