Involvement of the IL23/Th17 Pathway in the Pathogenesis of Tunisian Pemphigus Foliaceus

Figure 3

mRNA expression of IL23R and RORγt in peripheral blood (a) and skin biopsies (b). PBMCs were extracted from 5 de novo patients and 4 HC. Biopsies from de novo patients (), patients in the chronic stage (), and from HC () were analyzed using Q-PCR. The relative expression was estimated using 2^−ΔΔCt method and normalized to the average of the GAPDH housekeeping gene. value was calculated using Mann–Whitney U test.

(a)

(b)