Research Article

Association between Brain-Derived Neurotrophic Factor (BDNF) Levels in 2nd Trimester Amniotic Fluid and Fetal Development

Table 3

Distribution of BDNF (pg/ml) by fetal size group, including the extremes of distribution (divided into three subgroups for each 0th–10th and 90th–100th centile): significantly higher BDNF levels are observed in the amniotic fluid of severely growth-restricted fetuses (below 3rd centile).

Fetus of casesMean value

AGA3132,700
SGA < 10th centile3036,3000.09
SGA < 5th centile1836,9000.09
SGA < 3rd centile1040,8000.01
LGA > 90th centile1835,7000.22
LGA > 95th centile534,6000.65
LGA > 97th centile235,7000.53