Restoring Inflammatory Mediator Balance after Sofosbuvir-Induced Viral Clearance in Patients with Chronic Hepatitis C

Figure 1

Modulation of cytokines after antiviral therapy represented through (a) heatmaps and box plot graphics of (b) IL-1ra, TGF-β, IL-4, IL-10, IFN-γ, IL-1β; (c) IL-2, IL-6, IL-7, IL-15, CCL-2, CCL-3; (d) CCL-4, CCL-5, CCL-11, CXCL-10, CXCL-8, CSF-3; and (e) FGFb, PDGF-BB, VEGF, PAI-1, and suPAR serum levels at baseline and SVR. Dashed lines mean values of HCV noninfected controls. Statistical significance was assessed by Wilcoxon test or paired -test ().

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