Single Nucleotide Polymorphism in SMAD7 and CHI3L1 and Colorectal Cancer Risk

Table 12

Association studies of SNPs in SMAD7 gene and CRC.

Population	Reference SNP (rs)	Location	Association	Reference
African American and Caucasian	rs4939827	Intron 3	In women: yes	[166]
	rs4464148	Intron 3	Yes
Caucasian	rs12953717	Intron 3	Yes	[167]
	rs4939827	Intron 3	Yes
	rs4464148	Intron 3	No
Swedish	rs4939827	Intron 3	Yes	[168]
European	rs4464148	Intron 3	Yes	[169]
	rs4939827	Intron 3	No
Chinese	rs4939827	Intron 3	No	[170]
	rs12953717	Intron 3	Yes
	rs4464148	Intron 3	No
African American	rs4939827	Intron 3	Yes	[171]
Chinese	rs4939827	Intron 3	Yes	[76]
Romanian	rs4939827	Intron 3	CRC vs control: no	[172]
			Rectal vs colon cancer: yes
Caucasian	rs4939827	Intron 3	Yes	[173]
Croatian	rs4939827	Intron 3	Yes	[77]
Italian	rs4939827	Intron 3	Yes	[174]
Korean	rs4939827	Intron 3	Yes	[175]
Spanish	rs4939827	Intron 3	Yes	[176]
French	rs4939827	Intron 3	Yes	[177]
	rs58920878	Intron 3	Yes