How Adhesion Molecule Patterns Change While Neutrophils Traffic through the Lung during Inflammation

<div>Distribution of the adhesion molecules CD44 (a) and CD29 (b) on PMNs migrating through the different compartments of the lung. In the different compartments of the lung (IV = intravascular; ADHERENT = adherent to the endothelium; IS = interstitial; BAL = bronchoalveolar lavage) were the numbers of PMNs assessed that express the particular adhesion molecules (frequency of parents). By using the mean fluorescence intensity (MFI), the total amount of molecules on each PMN was evaluated and one representative histogram is shown, whereas the red histogram resembles the negative control. Data are presented as mean ± SD; <svg height="8.69875pt" id="M63" style="vertical-align:-0.3499298pt" version="1.1" viewbox="-0.0498162 -8.34882 53.8342 8.69875" width="53.8342pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M495 86L479 114C446 82 419 66 409 66C401 66 401 72 406 97C420 166 436 231 453 297C489 435 454 448 428 448C406 448 384 439 354 422C305 394 222 327 161 247H159L183 345C200 415 194 448 173 448C143 448 82 410 23 351L38 325C64 349 95 371 105 371C111 371 116 365 109 336L25 -4L31 -12C50 -4 77 3 107 9C119 69 132 122 145 168C197 254 321 381 370 381C387 381 393 374 378 305L329 95C309 17 320 -12 345 -12C372 -12 430 19 495 86Z"></path></g><g transform="matrix(.013,0,0,-0.013,10.158,0)"><path d="M535 323V373H52V323H535ZM535 138V188H52V138H535Z"></path></g><g transform="matrix(.013,0,0,-0.013,21.421,0)"><path d="M447 623H65C61 580 56 530 47 475H76C100 541 106 550 172 550H388C308 376 196 170 91 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Mediators of Inflammation

fig5

Figure 5

Figure 5: How Adhesion Molecule Patterns Change While Neutrophils Traffic through the Lung during Inflammation 