Quetiapine Attenuates the Neuroinflammation and Executive Function Deficit in Streptozotocin-Induced Diabetic Mice

Figure 1

QTP attenuated memory and executive function deficits of DM mice in a puzzle box test. (a) Latencies of mice in each group to complete the task in T1-T3. (b) Latencies of mice in each group to complete the task in T4-T6. (c) Latencies of mice in each group to complete the task in T7-T9. (d) Latencies of mice in each group to solve a new problem during the 3-day test (T1, T2, T5, and T8). (e) Latencies of mice in each group to solve a repeat new problem after 3-minute intervals during the 3-day test (short-term memory) (T3, T6, and T9). (f) Latencies of mice in each group to solve a repeat new problem after 24-hour intervals during the 3-day test (long-term memory) (T4 and T7). All data were expressed as . STZ vs. Cont; STZ+QTP vs. STZ, .

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