Quetiapine Attenuates the Neuroinflammation and Executive Function Deficit in Streptozotocin-Induced Diabetic Mice

Figure 2

QTP inhibited GFAP and CD11b protein expression level in the brain hippocampal tissues of DM mice. (a) Representative bar graph of GFAP expression and statistical results in mice of all groups. The protein level of GFAP in the STZ group was significantly higher than that in the control mice (), but the expression could be inhibited by QTP (). (b) Representative bar graph of CD11b expression and statistical results in the mice of all groups. The protein level of CD11b in the STZ group was significantly higher than that in the control mice (), but the expression could be inhibited by QTP (). All data were expressed as . vs. Cont; vs. STZ, .

(a)

(b)