Atorvastatin and Conditioned Media from Atorvastatin-Treated Human Hematopoietic Stem/Progenitor-Derived Cells Show Proangiogenic Activity In Vitro but Not In Vivo

Figure 2

Conditioned media from PAC stimulated with atorvastatin enhance the angiogenesis in the 2D Matrigel test but not in the 3D fibrin bead assay. HAoEC cells stimulated for 16 hours with conditioned media from PAC stimulated with atorvastatin or control, nonconditioned media with atorvastatin (a); number of junctions, vs. nonconditioned, ^$$ vs. DMSO, conditioned (b); number of meshes, vs. nonconditioned, ^$$ vs. DMSO, conditioned (c); number of segments, , vs. nonconditioned, ^$, ^$$, ^$$$ vs. DMSO, conditioned, two-way ANOVA with Bonferroni post hoc test, representative of 3 independent exp. (d); sprouting HAoEC cells on fibrin beads (e); an average number of sprouts (f); an average length of sprouts (g) ().

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