Research Article

Effect of Propofol on the Production of Inflammatory Cytokines by Human Polarized Macrophages

Figure 5

Propofol and muscimol enhanced nuclear translocation of Nrf2 in M1 THP-1 cells. (a) Immunoblotting analysis of the effects of propofol (50 μM) on nuclear translocation of Nrf2. (b) Densitometric analysis of bands in (a). (c) Immunoblotting analysis of the effects of muscimol (100 μM) on nuclear translocation of Nrf2. (d) Densitometric analysis of bands in (c). Data were normalized relative to lamin C (internal control for nuclear proteins) and presented as of four independent experiments. compared with control cells by one-way ANOVA with Bonferroni’s post hoc test or by the Wilcoxon-Mann-Whitney test.
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