Research Article
Remifentanil Protects against Lipopolysaccharide-Induced Inflammation through PARP-1/NF-κB Signaling Pathway
Figure 3
Remifentanil reduced PARP-1 expression and activity. PARP-1 expression and activity (PAR expression) were determined after stimulation. (a) RT-PCR result of PARP-1 mRNA expression. (b, c) Western blotting analysis of PARP-1 protein expression. (d, e) Western blotting analysis and quantification of PAR. Values are . versus control; # versus LPS+PBS. PARP-1: poly(ADP-ribose) polymerase 1; PAR: poly(ADP-ribose); LPS: lipopolysaccharide. .
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