Computational and Biological Comparisons of Plant Steroids as Modulators of Inflammation through Interacting with Glucocorticoid Receptor

Table 3

Effect of plant steroids and fluticasone on the adrenal and thymus gland indices in the cotton pellet-induced granuloma model.

Ligands	Adrenal index	Thymus index
Control	^a	^a
PC
PC-GA
PC-GS
PC-BA
PC-WA		^a
PC-DG
PC-FC	^a	^a

Values were expressed as () and analyzed by one-way ANOVA followed by Tukey’s test. Results were considered significant if values were less than 0.5. Results were considered significant if values were less than 0.5. ^aSignificant compared to positive control (PC). PC-GA: PC treated with glycyrrhetinic acid; PC-GS: PC treated with guggulsterone; PC-BA: PC treated with boswellic acid; PC-WA: PC treated with withaferin A; PC-DG: PC treated with diosgenin; PC-FC: PC treated with fluticasone.