FTY720 Effects on Inflammation and Liver Damage in a Rat Model of Renal Ischemia-Reperfusion Injury

Table 2

Lung tissue sections, stained with hematoxylin and eosin, were assessed using an established scoring system. Areas of pulmonary perivascular edema were scored based on the observed width of the arterial wall relative to the average width in uninjured tissues. A grading system describing the severity of edema was linked to the categorical scoring system based on this assessment as follows (see also Figure 1).

Grading scheme for pulmonary perivascular edema
Severity	Extent of edema	Grade	Quantifiable finding
Normal	None	0	None
Minimal	Very small amount	1	Up to 2 times the average width of the arterial wall
Mild	Small amount	2	3 to 5 times the average width of the arterial wall
Moderate	Moderate amount	3	6 to 7 times the average width of the arterial wall
Marked	Large amount	4	8 to 10 times the average width of the arterial wall
Severe	Very large amount	5	>10 times the average width of the arterial wall