Anti-TNF-α Monoclonal Antibody Therapy Improves Anemia through Downregulating Hepatocyte Hepcidin Expression in Inflammatory Bowel Disease

Figure 2

The serum levels of hepcidin are correlated with the severity of anemia in IBD patients. (a) The serum levels of hepcidin in UC patients with anemia () and UC patients without anemia (). (b) The serum levels of hepcidin in CD patients with anemia () and CD patients without anemia (). , , and . Data were expressed as , unpaired Student’s -tests. (c) Correlation between hepcidin and percents of LRL of Hb in UC patients (). (d) Correlation between hepcidin and percentages of LRL of Hb in CD patients (). (e) Correlation between hepcidin and serum iron in UC patients (). (f) Correlation between hepcidin and serum iron in CD patients (). (g) Correlation between hepcidin and serum ferritin in UC patients (). (h) Correlation between hepcidin and serum ferritin in CD patients (). Correlation analysis was performed by Spearman’s correlation analysis. values are shown in each panel.

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