Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15

Figure 1

Granzyme B expression in CD56^dim and CD56^bright NK cells. (a) A representative dotplot showing the gating of CD56^dim and CD56^bright NK cells stained with granzyme (above) and a representative histogram showing granzyme B expression in normal controls (normal) and SLE patients with active disease (active SLE) under the influence of IL-15 (below). (b) Comparison of the percentages of granzyme B expressing CD56^dim and CD56^bright NK cells among normal controls (normal), SLE patients with inactive disease (inactive SLE), and SLE patients with active disease.

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