Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15

Figure 5

Perforin (a) and granzyme B (b) expression of NKT-like cells from SLE and healthy controls under the influence of IL-15. A representative histogram comparing normal controls (normal) and SLE patients with active disease (active SLE) under the influence of IL-15 is shown (left). Comparison was also made among normal controls (normal), SLE patients with inactive disease (inactive SLE), and SLE patients with active disease (active SLE). PBMC were stimulated with or without IL-15 (10 ng/mL) for 18 hrs. Data was expressed as mean fluorescence intensity of positive cells. and (normal control, ; SLE with inactive disease, ; SLE with active disease, ).

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