Research Article

Cytotoxic Function and Cytokine Production of Natural Killer Cells and Natural Killer T-Like Cells in Systemic Lupus Erythematosis Regulation with Interleukin-15

Table 2

The percentages of IFN-γ and TNF-α expressing CD56dim and CD56bright NK cells in healthy controls (normal) and SLE patients with active and inactive disease.

IFN-γ (%)TNF-α (%)

CD56dim NK cellsNormalMedia67.7 ± 2.973.7 ± 2.5
IL-15
Inactive SLEMedia
IL-15
Active SLEMedia✝✝,##
IL-15,✝,✝,#
CD56bright NK cellsNormalMedia
IL-15
Inactive SLEMedia
IL-15
Active SLEMedia
IL-15✝,#

and compared to media; and ✝✝ compared to normal; # and ## compared to inactive SLE.