Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway

Figure 6

Detection of liver enzyme (ALT and AST) levels. The levels of ALT and AST were significantly decreased in the DC-IL10-treated group compared with the model group and DC-mock-treated group ( for all). Data represent of 8 mice in each group. values <0.05 were considered to be significant. G1, control group (); G2, model group (); G3, DC-mock-treated group (); G4, DC-IL10-treated group (). ALT: alanine transaminase; AST: aspartate transaminase.

(a)

(b)