Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-<i>β</i>/Smad Signaling Pathway

<div>Photomicrograph of a liver stained with MT stain (×100). The control group (G1) and DC-IL10-treated group (G4) showing normal distribution of collagen fibers in the portal areas. The model group (G2) showing marked fibrous bridging with excessive collagen fiber deposition. The DC-mock-treated group (G4) showing slight attenuation of collagen fibers distribution and deposition. G1: control group; G2: model group; G3: DC-mock-treated group; G4: DC-IL10-treated group.</div>

Mediators of Inflammation

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Figure 8: Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-<i>β</i>/Smad Signaling Pathway 

Figure 8 | Interleukin 10 Gene-Modified Bone Marrow-Derived Dendritic Cells Attenuate Liver Fibrosis in Mice by Inducing Regulatory T Cells and Inhibiting the TGF-β/Smad Signaling Pathway 