Tobacco-Derived Lipopolysaccharide, Not Microbial Translocation, as a Potential Contributor to the Pathogenesis of Rheumatoid Arthritis

Table 3

Correlations between disease indicators and the various test biomarkers.

		LPS			LBP			SP-D	I-FABP
		All	NTU	TU	All	NTU	TU
aCCP-IgG		0.3930	0.3674	ns	0.2770	ns	0.5088	ns	ns
		0.0133	0.0846		0.0836		0.0442
aCCP-IgA		ns			ns		ns
	RF-IgM										0.4731
							0.0642
RF-IgA							ns
	RF-IgG										0.5324	0.3938	ns	0.5157
							0.0334			0.0119	0.0409

Key: aCCP—anticyclic citrullinated peptide; RF—rheumatoid factor; Ig—immunoglobulin; LPS—lipopolysaccharide; LBP—LPS-binding protein; SP-D—surfactant protein D; I-FABP—intestinal fatty acid-binding protein; NTU—nontobacco usage; TU—tobacco usage; ns—not significant.