Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection

Figure 3

Induction of IRF1, IRF3, and IRF7 mRNA in HMPV-infected airway epithelial and immune cells. Cells were infected with HMPV for 24 h. Gene expression was analyzed by qRT-PCR. Expression was normalized relative to GAPDH. Data are presented as of 3 (A549 cells) or 2 (NECs, MDMs, and MDDCs) independent experiments. (a) IRF1, (b) IRF3, and (c) IRF7 mRNA. Statistical analysis (one-sided ANOVA with Dunnett’s test): (), (), and (); comparisons were made between noninfected and infected cells.

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