Cell-Type-Specific Transcription of Innate Immune Regulators in response to HMPV Infection

Figure 5

Effect of HMPV on MDA5 and RIG-I gene expression in airway epithelial and immune cells. Cells were infected with HMPV for the indicated time points. Levels of mRNA were analyzed by qRT-PCR. Cells were infected for the indicated time points with HMPV. Gene expression was analyzed by qRT-PCR. Expression was normalized relative to GAPDH. Data are presented as of 3 (a) or 2 (b-d) independent experiments. (a) A549, (b) NEC, (c) MDM, and (d) MDDC. (a-d) Statistical analysis (one-sided ANOVA with Dunnett’s test): (), (), and (); comparisons were made between noninfected and infected cells.

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