MicroRNA Expression in Cutaneous Lupus: A New Window to Understand Its Pathogenesis

Table 2

Multiple linear regression models for patients with SCLE.

	Model	miRNAs		square			Sig. ()	95% IC for
								Lower	Up
Peripheral cells
CD3^+/CD4^+/CD25^-/IL-4^+	1	miR-23b	0.493	0.244	-0.493	-2.407	0.027	-0.901	-0.061
CD3^+/CD4^+/CD25^+/IFN-γ^+	1	miR-1246	0.431	0.186	-0.431	-2.908	0.006	-0.399	-0.071
CD3^+/CD4^+/CD25hi/Foxp3^+	1	miR-23b	0.449	0.201	-0.449	-2.13	0.047	-1.47	-0.01
Tissue cells
IL-4-expressing CD4^+ cells (epidermis)	1	miR-21	0.487	0.237	0.487	2.365	0.029	0.425	7.171
IFN-γ-expressing CD4^+ cells (dermis)	1	miR-31	0.467	0.218	0.467	2.238	0.038	0.717	22.62
IL-10-expressing CD20^+ cells (epidermis)	1	miR-21	0.492	0.242	0.492	2.396	0.028	0.61	9.298

SCLE: subacute cutaneous lupus erythematosus; DLE: discoid lupus erythematosus; HD: healthy donors.