Hepcidin and Iron Homeostasis in Patients with Subacute Thyroiditis and Healthy Subjects

Figure 1

The stimulators and inhibitors of hepcidin in iron homeostasis. The clinical factors and level of iron in the serum impact the secretion of hepcidin. The stimulators increase concentration of hepcidin, inhibiting iron transfer from the lumen of the duodenum to the serum, from ion storage in the hepatocytes and macrophages located in the spleen. The inhibitors act antagonistically.