Flemingia philippinensis Flavonoids Relieve Bone Erosion and Inflammatory Mediators in CIA Mice by Downregulating NF-κB and MAPK Pathways

Figure 3

Effect of prophylactic administration of FPF on antibody response to CII in CIA mice. Starting at day 7 after the CII challenge, gavage was performed daily with water and 40 mg/kg FPF until day 46 on the mice. The mice were euthanized, and their plasma was collected for measurement of IgG, IgG1, IgG2a, and IgM against CII. Bar represent plasma concentrations. compared with the vehicle group by Student’s -test.

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