PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes

Figure 2

PG102 upregulates IL-37 expression in HaCaT cells. (a) PG102 (1 mg/mL) was treated to HaCaT cells at different time points, followed by RNA extraction and RT-qPCR analysis. (b) HaCaT cells were treated with PG102 at different concentrations for 24 hours, followed by RT-qPCR analysis. (c) HaCaT cells were treated with PG102 at different concentrations for 48 hours, followed by Western blot analysis. Representative results from three independent experiments are shown. Each point represents . , versus control cells.

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