Enhanced Endothelin A and B Receptor Expression and Receptor-Mediated Vasoconstriction in Rat Mesenteric arteries after Lipopolysaccharide Challenge

<div>Hematoxylin-eosin staining and immunohistochemical staining on paraffin-embedded tissue sections showed the morphology of the vessels and the upregulation of ET<sub>A</sub> and ET<sub>B</sub> after LPS treatment, respectively. Arteries (without endothelium) were taken from rats treated with NS or LPS (5 mg/kg body weight) for 6 hrs. The arrowhead points to the positive staining of ET<sub>A</sub> or ET<sub>B</sub> protein. L: lumen. The size bar corresponds to 200 <i>μ</i>m (150x) or 50 <i>μ</i>m (600x. (b, c) Semiquantitation of immunohistochemistry results by using ImageJ software. 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598 226 604C236 612 262 617 304 617C371 617 429 604 474 576C554 529 592 439 592 336C592 176 505 36 319 36C246 36 213 55 213 131V547Z"></path></g></svg>.</span> Unpaired Student’s <span class="nowrap"><svg height="8.02022pt" id="M40" style="vertical-align:-0.2063999pt" version="1.1" viewbox="-0.0498162 -7.81382 4.54925 8.02022" width="4.54925pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M324 430H196L233 583L223 592L145 529L120 430H54L29 396L31 388H111L56 126C33 15 54 -12 77 -12C137 -12 214 57 250 95L233 119C208 92 155 59 138 59C126 59 120 70 131 125L186 390L298 394L324 430Z"></path></g></svg>-</span>test, <svg height="10.7395pt" id="M41" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -10.1025 80.1879 10.7395" width="80.1879pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.0091,0,0,-0.0091,0,-5.741)"><path d="M486 158C486 177 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Enhanced Endothelin A and B Receptor Expression and Receptor-Mediated Vasoconstriction in Rat Mesenteric arteries after Lipopolysaccharide Challenge 

Figure 3 | Enhanced Endothelin A and B Receptor Expression and Receptor-Mediated Vasoconstriction in Rat Mesenteric arteries after Lipopolysaccharide Challenge 