PPAR-γ Activation Exerts an Anti-inflammatory Effect by Suppressing the NLRP3 Inflammasome in Spinal Cord-Derived Neurons

Figure 1

Representative HE staining of the rat spinal cord after SCI. (a1) Spinal cord hyperemia and central tube structural disorder was observed in the transverse section of the spinal cord on the 1st day after SCI (10x); (a2) in the transverse section of the ventral horn on the 1st day after SCI, red blood cells infiltrated around neurons (20x). (b1) A syringomyelia was forming in the transverse section of the spinal cord on the 7th day after SCI (10x); (b2) in the transverse section of the ventral horn on the 7th day after SCI, we observed survival of neural cell bodies and increasing gaps among myelin sheaths (20x). (c1) The syringomyelia had formed in the transverse section of the spinal cord on the 28th day after SCI (10x); (c2) in the transverse section of the ventral horn on the 28th day after SCI, we observed survival of neural cells and larger gaps among myelin sheaths (20x).

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