Evidence That the Anti-Inflammatory Effect of Rubiadin-1-methyl Ether Has an Immunomodulatory Context

Figure 3

Effect of Rubiadin-1-methyl ether at 30 μM dose on NOx (a), IL-6 (b), IL-1β (c), and TNF-α secretion (d) in RAW 264.7 macrophages stimulated with LPS. B: cells pretreated with vehicle and stimulated with PBS; LPS: cells stimulated with LPS (1 μg/mL); Dexa: cells pretreated with Dexamethasone (7 μM) and stimulated with LPS (1 μg/mL); Rub: cells pretreated with Rubiadin-1-methyl ether at 30 μM and stimulated with LPS (1 μg/mL). The results were expressed as the ; ; and compared with the LPS group.

(a)

(b)

(c)

(d)