Mediators of Inflammation

Research Article

The Acute Phase Proteins Reaction in Children Suffering from Pseudocroup

Table 2

Results of the investigations of acute phase protein (APP) concentrations and glycosylation profiles for the control group and study group at the 3 time points (statistically significant differences are marked in bold; the Mann–Whitney U test value and value are given).
APPControl group ()Sample 1
Me (Q25-Q75)		Difference with the control groupSample 2
Me (Q25-Q75)		Difference with the control groupSample 3
Me (Q25-Q75)		Difference with the control group
CRP0 (0)0 (0-3)1.37
0.17		0 (0)-0.43
0.67		0 (0)0.04
0.97
AGP870 (630-1000)950 (720- 1230)0.99
0.32		985 (800-1200)1.39
0.16		785 (570-990)-1.19
0.24
AGP-W0%50.0 (45.4-52.5)44.9 (41.4-48.5)-2.82
0.005		46.3 (42.2-49.6)-2.27
0.02		47.9 (42.3-51.0)-1.19
0.23
AGP-W1%42.7 (40.6-43.9)38.8 (36.8-42.7)-2.99
0.003		39.3 (38.0- 42.7)-2.71
0.01		39.9 (37.0-42.5)-2.90
0.004
AGP-W2%6.6 (5.5-8.0)11.9 (8.4-15.0)4.49
0.00001		10.5 (8.6- 13.4)4.41
0.00		10.3 (7.3- 13.0)3.74
0.0002
AGP-W3%0.6 (0-1.9)3.3 (1.9-5.3)3.76
0.0002		2.8 (0-5)2.77
0.01		2.2 (0-5.2)1.68
0.09
AGP-RC1.0 (0.9-1.2)1.2 (1.1-1.4)2.83;
0.005		1.2 (1.0-1.4)2.24
0.025		1.1 (1.0-1.4)1.24
0.22
ACT340 (290-400)380 (290-470)1.03
0.303		390 (310-550)1.42
0.16		313 (240-350)-1.82
0.07
ACT-A1%22.5 (19.4-25.8)22.6 (18.5-25.5)-0.73
0.467		23.1 (19.1-25.7)-0.31
0.76		24.9 (23.5-27.0)1.27
0.21
ACT-A2%31.8 (29.2- 34.3)29.1 (25.9- 31.3)-2.51
0.012		29.8 (26.8- 31.7)-1.71
0.09		30.3 (27.1- 31.9)-1.70
0.09
ACT-A3%22.6 (15.8- 24.6)22.5 (18.5-29.4)1.37
0.171		22.3 (18.3- 28.0)0.83
0.41		20.9 (17.3- 26.6)0.42
0.67
ACT-A4%20.8 (18.4- 25.6)18.2 (12.9- 20.9)-1.98
0.047		17.1 (11.3- 23.2)-1.89
0.06		12.9 (9.1- 19.3)-3.39
0.001
ACT-A5%2.9 (0-4.4)4.8 (0-8.9)1.76
0.08		5.1 (3.9-7.6)2.20
0.03		6.9 (4.0-12.0)3.63
0.001
ACT-RC3.5 (2.9- 4.2)3.4 (2.9- 4.4)0.72
0.474		3.3 (2.9- 4.3)0.32
0.75		3.0 (2.7- 3.3)-1.28
0.201
Tf2725 (2270- 3040)2240 (1810- 2700)-2.68
0.007		2295 (1830- 2720)-2.37
0.018		2220 (1810- 2720)-2.375
0.018
Tf-T1%4.0 (3.4–6.2)5.9 (4.6-7.8)2.43
0.015		5.6 (3.9-7.6)1.50
0.13		5.4 (4.0-6.6)1.24
0.24
Tf-T2%14.3 (12.7–18.9)18.6 (15.2-21.1)2.52
0.012		18.3 (16.7-21.2)2.84
0.004		18.7 (14.3-22.2)1.97
0.05
Tf-T3%73.4 (62.5-78.3)70.5 (62.1-74.0)-1.33
0.18		70.6 (65.7-73.6)-0.95
0.34		71.3 (65.9-76.1)-0.52
0.61
Tf-T4%5.7 (4.6-13.9)3.9 (2.3-7.8)-2.77
0.001		3.2 (2.2-6.4)-3.58
0.0003		3.2 (2.2-7.8)-2.74
0.01
A2M5.2 (4.9-5.6)5.0 (3.8-5.6)-1.72
0.085		4.8 (4.0-5.5)-2.10
0.034		4.9 (4.1-5.4)-1.80
0.072
Cp455 (400-540)510 (380-620)1.01
0.312		477 (390-542)0.26
0.797		489 (430-600)1.24
0.213
Hp1.0 (0.8-1.3)0.9 (0.7-1.4)-0.32
0.745		1.2 (0.8-1.5)1.32
0.187		0.7 (0.4-1.1)-2.54
0.011
AT2.0 (1.9-2.1)1.8 (1.5-2.2)-1.86
0.063		1.8 (1.6-2.2)-1.69
0.089		1.6 (1.3-2.0)-3.41
0.001