miR-155 Predicts Long-Term Mortality in Critically Ill Patients Younger than 65 Years

Figure 3

Serum concentrations of ICU predict long-term survival specifically in young ICU patients. (a) miR-155 serum levels in patients younger or older than 65 years. (b, c) Kaplan-Meier curve analysis demonstrating that years (but not older patients) with miR-155 concentrations below the median of all patients had an increased overall mortality. (d) The Youden index was used to calculate the optimal threshold for distinguishing between long-term survivors and patients that did not survive in the group of years old. Kaplan-Meier survival curve analyses revealed that patients with miR-155 concentrations below this threshold had an increased overall mortality. (e) Kaplan-Meier curve analysis was performed in years old, revealing that the mortality of these patients was independent of their miR-155 serum concentration. (f) ROC curve analysis revealing that miR-155 serum levels display a superior prognostic value in critically ill patients younger than 65 years. .

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