Calprotectin and Calgranulin C as Biomarkers of Pancreatic Tumors: Baseline Levels and Level Changes after Surgery

Table 4

AUCs, cutoff values, sensitivities, and specificities of the biomarkers for the prediction of surgical complications.

	AUC	Threshold	Sensitivity	Specificity
Day 1
Calprotectin (ng/mL)	0.6324	6177.25	0.5000	0.7297
Calgranulin C (ng/mL)	0.6072	97.66	0.4333	0.8378
WBC count ()	0.5268	12.05	0.6833	0.4595
CRP (mg/L)	0.5747	129.65	0.7755	0.4118
AMS (μkat/L)	0.8240	7.67	0.6842	0.8621
Day 3
Calprotectin (ng/mL)	0.7780	9987.50	0.7049	0.8108
Calgranulin C (ng/mL)	0.7873	182.12	0.6230	0.8649
WBC count ()	0.6645	10.72	0.5763	0.7297
CRP (mg/L)	0.7151	206.30	0.8621	0.5676
AMS (μkat/L)	0.8429	3.77	0.8974	0.6571
Day 5
Calprotectin (ng/mL)	0.7707	11049.5	0.7000	0.8108
Calgranulin C (ng/mL)	0.7423	254.80	0.7500	0.7297
WBC count ()	0.6289	13.81	0.9322	0.2941
CRP (mg/L)	0.7638	76.30	0.6964	0.7879
AMS (μkat/L)	0.8171	0.62	0.7632	0.7742
Day 7
Calprotectin (ng/mL)	0.8163	11693.25	0.7037	0.7838
Calgranulin C (ng/mL)	0.7815	297.50	0.8148	0.6757
WBC count ()	0.6694	14.98	0.9348	0.3824
CRP (mg/L)	0.7216	51.70	0.6136	0.8125
AMS (μkat/L)	0.8852	0.94	0.8182	0.9474

AUC: area under the ROC curve; WBC: white blood cell; CRP: C-reactive protein; AMS: amylase.