Mediators of Inflammation

Research Article

The Potential Role of Matrix Metalloproteinases 8 and 9 and Myeloperoxidase in Predicting Outcomes of Bacterial Meningitis of Childhood

Table 3

Correlation matrix for the studied molecules^a.


Variable	MPO	MMP-8	TIMP-1	Total MMP-9	Act% of MMP-9	MMP8/TIMP-1 molar ratio

MPO	N/A	0.496	-0.361	0.153	0.128	0.528
MPO	N/A
MMP-8	0.496	N/A	-0.052	0.160	0.051	0.556
MMP-8		N/A
TIMP-1	-0.361	-0.052	N/A	-0.052	-0.158	-0.476
TIMP-1			N/A
Total MMP-9	0.153	0.160	-0.052	N/A	0.570	0.186
Total MMP-9				N/A
Act% of MMP-9	0.128	0.051	-0.158	0.570	N/A	0.108
Act% of MMP-9					N/A
MMP8/TIMP-1 molar ratio	0.528	0.556	-0.476	0.186	0.108	N/A
MMP8/TIMP-1 molar ratio						N/A

^aCorrelations were calculated using Spearman’s rank correlation. Significant correlations are in bold. Act% of MMP-9 represents the percentual expression of the active form of MMP-9.