Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between <i>β</i>2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells

<div>Effect of agonists on the expression of <i>β</i>2-AR and TLR4 in HPMECs. (a) Effect of agonists on the cell surface expression of proteins in HPMECs. The representative blots show the expression of <i>β</i>2-AR (A, upper), TLR4 (A, middle), and Na<sup>+</sup>-K<sup>+</sup>-ATPase (A, lower). The histograms illustrate the quantitative analysis of the <i>β</i>2-AR and TLR4 protein levels normalized to Na<sup>+</sup>-K<sup>+</sup>-ATPase. (b, c) Expression of inflammatory factors (IL-6, IL-17A, IL-8, and TNF-<i>α</i>) after treatment with ISO and LPS. (d) Effect of ISO and LPS treatment on monolayer permeability. 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between <i>β</i>2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells 

Figure 3 | Endothelial Cell Inflammation and Barriers Are Regulated by the Rab26-Mediated Balance between β2-AR and TLR4 in Pulmonary Microvessel Endothelial Cells 