Application of Cerebrospinal Fluid Host Protein Biosignatures in the Diagnosis of Tuberculous Meningitis in Children from a High Burden Setting

Table 1

Clinical and demographic characteristics of children included in the study.

	All	TBM	No TBM^#
Number of participants	47	23	24
Median age, months (IQR)	22.0 (10.5-57.0)	18.0 (11.0-40.0)	30.0 (9.0-96.0)
Males, (%)	30 (63.8)	13 (56.5)	17 (70.8)
HIV-positive, /not tested	6/37	0/22	6/15

^#The no TBM group included children with bacterial meningitis (), viral meningitis (), asphyxia (), autoimmune encephalitis (), febrile seizure (), Guillain Barre (), HIV encephalopathy (), focal seizures (), leukemia (), miliary TB (with lymyphocytic interstitial pneumonitis) (), developmental delay (), breakthrough seizure (), gastroenteritis (caused by shock) (), idiopathic intracranial hypertension (IIH) (), viral gastroenteritis (adeno and rota) and encephalopathy (), stroke (), mitochondrial diagnosis (), viral pneumonia (this included also SAM and nosocomial sepsis) (), febrile seizure and acute gastroenteritis (), and others (). IQR: interquartile range.