Preoperative Sleep Disturbance Exaggerates Surgery-Induced Neuroinflammation and Neuronal Damage in Aged Mice

Figure 5

Preoperative sleep disturbance accelerated surgery-induced astrocyte activation in the hippocampus. (a) Representative images of activated astrocytes in areas CA1 and CA3 of the hippocampus based on staining with an anti-GFAP antibody. Scale bar: 100 μm. (b) Quantification of GFAP-positive cell areas CA1 and CA3 of the hippocampus. (c) Expression levels of GFAP protein. The data are presented as the (). and vs. the Con group; and vs. the Sur group.

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