Research Article
Increased Soluble Epoxide Hydrolase in Human Gestational Tissues from Pregnancies Complicated by Acute Chorioamnionitis
Figure 7
Administration of AUDA reduced the levels of 14,15-DHET, IL-1β, and IL-6 in the placentas of pregnant mice treated with LPS. Compared to the sham controls, pregnant mice treated with LPS had significantly higher levels of 14,15-DHET, IL-1β, and IL-6 in the placentas. Administration of AUDA significantly reduced the extent of these changes caused by LPS. Data are presented as based on 8 mice for each group. and compared with the sham controls; # and ## compared with mice treated with LPS, with one-way ANOVA followed by Bonferroni’s post hoc test.
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