Synovial Macrophages in Rheumatoid Arthritis: The Past, Present, and Future

Figure 1

The markers comparison of resident SMs and bone marrow-derived SMs. (a) Resident SM markers include Z39Ig, CD68, CD163, MerTK, 25F9, F4/80, and ED2/3 (rat); (b) Bone marrow-derived SM markers include CD16, CD11b, CD14, MRP8/14, CCR2, Ly6C, MMR, MPO, lysozyme, and ED1 (rat). Up to now, these are several regulatory agents of resident SMs (SIN) and bone marrow-derived SMs. (NFAT5, Sirt6, miR-146a, MRP8/14, and Withaferin-A).