Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression

Figure 1

CD39 and CD73 concentrations in PFP samples from NDs and patients with LSILs, HSILs, or CC. The type curves for soluble CD39 and CD73 were established by ELISA using different concentrations (5-30 ng/ml) of human recombinant proteins CD39 (rhCD39) (a) and CD73 (rhCD73) (c), whose correlations with absorbance (optical density) were () and (), respectively. For the detection of CD39 and CD73, the PFP samples of the NDs and women with LSILs, HSILs, or CC were diluted with PBS at ratios of 1 : 40,000 and 1 : 25,000, respectively. The data are representative of three independent experiments. The of the concentrations of soluble CD39 (b) and CD73 (d) detected in the PFP of the NDs and patients with LSILs, HSILs, or CC are shown. Significant differences are indicated by (), (), and (). ns: not significant.

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