Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression

<table class="table-group" id="tab4"><tr><td><table class="table"><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr class="thead"><td class="align_left" rowspan="2">Nucleotidase</td><td class="align_center" colspan="3">Normal donors</td><td class="align_center" colspan="3">SIL patients</td><td class="align_center" rowspan="2"><svg height="10.2124pt" id="M104" style="vertical-align:-3.42943pt" version="1.1" viewbox="-0.0498162 -6.78297 7.83752 10.2124" width="7.83752pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M570 304C570 398 525 448 414 448C385 448 343 445 312 434L329 511L321 518C297 504 262 482 244 460L233 411C195 397 159 381 128 358L135 332C160 347 189 360 224 373L111 -147C97 -210 84 -218 17 -231L13 -257L254 -247L259 -218L233 -216C183 -212 177 -202 189 -142L218 -1C238 -10 266 -12 283 -12C351 3 429 48 483 105C543 168 570 242 570 304ZM482 289C482 161 380 33 304 33C278 33 248 51 233 69L303 396C326 400 352 403 369 403C428 403 482 380 482 289Z"></path></g></svg> values</td></tr><tr class="thead"><td class="align_center">Age (years)</td><td class="align_center">Number of sexual partners</td><td class="align_center">Number of pregnancies</td><td class="align_center">Age (years)</td><td class="align_center">Number of sexual partners</td><td class="align_center">Number of pregnancies</td></tr><tr><td class="thead-hr" colspan="8"><hr/></td></tr><tr><td class="align_left">CD39</td><td class="align_center">-0.06017</td><td class="align_center">-0.2257</td><td class="align_center">0.0721</td><td class="align_center">0.1308</td><td class="align_center">0.3312<sup>a</sup></td><td class="align_center">0.3512<sup>b</sup></td><td class="align_center" rowspan="2"><span style="width: 55.0434ptpx;"><svg height="8.98582pt" id="M105" style="vertical-align:-0.6370001pt" version="1.1" viewbox="-0.0498162 -8.34882 55.0434 8.98582" width="55.0434pt" xmlns="http://www.w3.org/2000/svg" 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transform="matrix(.013,0,0,-0.013,0,0)"><path d="M517 51L485 54C448 58 441 63 441 115V712C404 700 337 684 285 678V653C357 648 362 645 362 580V437C339 446 309 449 295 449C159 449 38 340 38 201C38 61 143 -12 223 -12C234 -12 261 -6 301 17L362 53V-12C420 9 495 22 517 26V51ZM362 85C338 67 301 51 266 51C201 51 128 109 128 228C128 373 212 411 259 411C296 411 338 395 362 360V85Z"></path></g><g transform="matrix(.013,0,0,-0.013,10.522,0)"><path d="M512 -3V55L134 254V256L512 456V514L75 281V230L512 -3Z"></path></g><g transform="matrix(.013,0,0,-0.013,21.784,0)"><path d="M241 635C89 635 35 457 35 312C35 153 89 -12 240 -12C390 -12 443 166 443 312C443 466 390 635 241 635ZM238 602C329 602 354 454 354 312C354 172 330 22 240 22C152 22 124 173 124 313S148 602 238 602Z"></path></g><g transform="matrix(.013,0,0,-0.013,28.024,0)"><path d="M113 -12C146 -12 170 11 170 46C170 78 146 103 114 103S58 78 58 46C58 11 82 -12 113 -12Z"></path></g><g transform="matrix(.013,0,0,-0.013,30.988,0)"><path d="M241 635C89 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class="align_center">0.3028</td><td class="align_center">0.2277</td><td class="align_center">0.2284</td><td class="align_center">0.5868<sup>c</sup></td><td class="align_center">0.1542</td><td class="align_center">0.6387<sup>d</sup></td></tr><tr class="table-tr"><td colspan="8"><hr class="tbody-hr"/></td></tr></table></td></tr><tr class="table-fn"><td><div>Values of Pearson’s coefficient (<span class="nowrap"><svg height="6.1673pt" id="M109" style="vertical-align:-0.2063904pt" version="1.1" viewbox="-0.0498162 -5.96091 5.60619 6.1673" width="5.60619pt" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink"><g transform="matrix(.013,0,0,-0.013,0,0)"><path d="M393 379C402 394 400 411 393 422C384 437 365 448 348 448C301 448 237 372 186 285H182L193 335C210 408 205 448 178 448C150 448 80 402 29 344L45 321C80 355 114 373 122 373C128 373 130 365 124 330C106 228 76 98 50 -5L57 -12C82 -5 112 3 132 6L172 203C196 256 234 304 254 329C275 355 293 367 306 367C318 367 330 360 342 348C347 343 355 343 365 350S386 367 393 379Z"></path></g></svg>)</span> are shown.<br/></div></td></tr></table>

<div>Correlation analysis of the clinical data of normal donors and patients with SIL and the plasmatic contents of the nucleotidases CD39 and CD73.</div>

Mediators of Inflammation

tab4

Table 4

Table 4: Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression 

Table 4 | Detection of CD39 and a Highly Glycosylated Isoform of Soluble CD73 in the Plasma of Patients with Cervical Cancer: Correlation with Disease Progression 