Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury

<div>Effect of GSK484 on the PAD4 expression and citH3 accumulation in the lung after renal IR. (a, b) Representative images of immunohistochemical staining and analysis of PAD4-positive cells in lung sections from different groups (scale bar: 50 <i>μ</i>m). (c, d) Immunofluorescence images and analysis of H3cit-positive cells in the lung (scale bar: 20 <i>μ</i>m). 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Mediators of Inflammation

fig3

Figure 3

Figure 3: Inhibition of Peptidyl Arginine Deiminase-4 Prevents Renal Ischemia-Reperfusion-Induced Remote Lung Injury 