Mediators of Inflammation

Research Article

CD4⁺ T Cell Profile and Activation Response in Sickle Cell Disease Patients with Osteonecrosis

Table 3

Lymphocyte frequencies (%) in PB-MNC.


	Control	SCD	SCD/ON	value
	Control	SCD	SCD/ON	Control vs. SCD	Control vs. SCD/ON	SCD vs. SCD/ON

TCD4⁺	42.0 (19.2-61.6)	21.4 (5.7-47.5)	30.0 (8.4-59.7)	0.0074	0.0442	0.2854
TCD8⁺	24.0 (14.1-38.7)	12.5 (4.8-23.7)	14.6 (2.6-23.9)	0.0085	0.0020	0.5962
TCD4⁺/45RO⁺	21.6 (4.8-41.3)	10.8 (4.3-16.1)	15.5 (4.6-25.6)	0.0154	0.1541	0.1892
TCD4⁺/45RA⁺	40.3 (20.8-59.4)	10.8 (2.3-28.6)	12.60 (2.4-25.0)	0.0003	<0.0001	0.8749

All values are presented in median. Significance values are presented as , , , and .