Research Article
The Expression of IL-12 Family Members in Patients with Hypertension and Its Association with the Occurrence of Carotid Atherosclerosis
Table 1
Clinical characteristics of hypertensive patients and control subjects.
| | Characteristics | Control | Hypertension | | Total | Grade I | Grade II | Grade III |
| | Male (, %) | 37 (49.3) | 241 (56.0) | 124 (53.0) | 76 (60.3) | 41 (58.6) | | Elderly (, %) | 18 (24.0) | 151 (35.1) | 89 (38.0) | 49 (38.9) | 13 (18.6)#&$ | | Overweight (, %) | 17 (22.7) | 281 (65.3) | 144 (61.5) | 88 (69.8) | 49 (70.0) | | Smoking (, %) | 23 (30.7) | 155 (36.0) | 79 (33.8) | 52 (41.3) | 24 (34.3) | | Drinking (, %) | 13 (17.3) | 110 (25.6) | 54 (23.1) | 39 (31.0) | 17 (24.3) | | Dipper (, %) | — | 209 (48.6) | 111 (47.4) | 65 (51.6) | 33 (47.1) | | T2DM (, %) | 5 (6.7) | 114 (26.5) | 58 (24.8) | 40 (31.7) | 16 (22.9) | | HLP (, %) | 17 (22.6) | 241 (56.0) | 123 (52.6) | 61 (48.4) | 36 (51.4) | | ASHS (, %) | 0 (0.0) | 52 (12.1) | 26 (11.1) | 21 (16.7) | 5 (7.1) | | Hypoxemia (, %) | 0 (0.0) | 49 (11.4) | 26 (11.1) | 20 (15.9) | 3 (4.3) | | CAP (, %) | 0 (0.0) | 153 (35.6) | 65 (27.8) | 50 (39.7) | 38 (54.3)& | | Age (years) | | | | | #&$ | | BMI (kg/m2) | | | # | & | | | HR (bpm) | | | # | & | #& | | SBP (mmHg) | | | # | #& | #&$ | | DBP (mmHg) | | | # | #& | #&$ | | Glu (mmol/L) | | | | | | | HbAlc (%) | | | | | | | Insulin (μU/mL) | | | | | | | TC (mmol/L) | | | | | #& | | TG (mmol/L) | | | | | | | HDL-C (mmol/L) | | | | | | | LDL-C (mmol/L) | | | | | & | | CREA (μmol/L) | | | | | #&$ | | UA (μmol/L) | | | | | | | CK-MB (U/L) | | | | | | | CRP (mg/L) | | | | | | | tHcy (μmol/L) | | | | | #& | | Medical treatments (, %) | | ACEI/ARB | 5 (6.7) | 241 (56.0) | 131 (56.0) | 75 (59.5) | 35 (50.0) | | β-Blocker | 5 (6.7) | 181 (42.1) | 101 (41.2) | 49 (38.9) | 31 (44.3) | | CCB | 0 (0.0) | 297 (69.1) | 161 (68.8) | 85 (67.5) | 51 (72.9) | | Diuretics | 0 (0.0) | 126 (29.3) | 62 (26.5) | 45 (35.7) | 19 (27.1) | | α-Blocker | 2 (2.6) | 27 (6.3) | 12 (5.1) | 9 (7.1) | 6 (8.6) |
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T2DM: type 2 diabetes mellitus; HLP: hyperlipidemia; ASHS: sleep apnea hypopnea syndrome; CAP: carotid atherosclerotic plaque; BMI: body mass index; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; Glu: fasting glucose; HbAlc: hemoglobin a1c; TC: total cholesterol; TG: total triglycerides; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; CREA: creatinine; UA: uric acid; CK-MB: creatine kinase myocardial band; CRP: C-reactive protein; tHcy: plasma total homocysteine; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker. vs. control group; # vs. total group; & vs. grade I group; $ vs. grade II group. |
