The Expression of IL-12 Family Members in Patients with Hypertension and Its Association with the Occurrence of Carotid Atherosclerosis

Table 8

Association between serum IL-12, IL-23, IL-27, and IL-35 levels and the presence of CAP was assessed by univariate analysis and subsequent multivariate linear regression analysis.

Variables	Univariate			Multivariate
		95% CI	value		95% CI	value
IL-12	0.343	0.257 to 0.430	<0.001	0.120	0.023 to 0.217	0.016
IL-23	0.417	0.334 to 0.501	<0.001	0.156	0.052 to 0.261	0.003
IL-27	0.370	0.285 to 0.456	<0.001	0.114	0.010 to 0.219	0.032
IL-35	-0.374	-0.459 to -0.289	<0.001	-0.160	-0.254 to -0.066	0.001
Male	0.101	0.009 to 0.192	0.031	0.013	-0.079 to 0.106	0.775
Elderly	0.125	0.034 to 0.216	0.007	0.142	0.062 to 0.222	0.001
Overweight	0.126	0.035 to 0.217	0.007	0.030	-0.053 to 0.112	0.482
Smoking	0.072	-0.020 to 0.163	0.124
Drinking	0.125	0.034 to 0.216	0.007	0.076	-0.010 to 0.161	0.084
Nondipper	0.208	0.119 to 0.298	<0.000	0.133	0.053 to 0.212	0.001
T2DM	0.121	0.030 to 0.212	0.009	0.019	-0.063 to 0.102	0.644
HLP	0.171	0.080 to 0.261	<0.000	0.074	-0.008 to 0.155	0.076
SAHS	0.171	0.080 to 0.261	<0.000	0.283	0.044 to 0.521	0.020
Hypoxemia	0.130	0.039 to 0.221	0.005	-0.177	-0.414 to 0.061	0.145
CRP	0.025	-0.067 to 0.117	0.597
tHcy	0.131	0.040 to 0.222	0.005	0.032	-0.053 to 0.118	0.455