Research Article

The Effects of Sidt2 on the Inflammatory Pathway in Mouse Mesangial Cells

Figure 1

Establishment of a Sidt2 knockout cell model and morphological observation. (a) The level of mRNA in the Sidt2-/- group was significantly lower than that in the Sidt2+/+ group. (b c) The expression of Sidt2 in the Sidt2-/- group was significantly decreased by western blotting compared with that in the Sidt2+/+ group. (d) Hematoxylin and eosin staining revealed different cellular states between the Sidt2-/- group and the Sidt2+/+ group. The cell body of the Sidt2-/- group was significantly smaller than that of the Sidt2+/+ group (arrow), and the nuclear pyknosis and fragmentation were blue-black (triangle). , compared with the Sidt2+/+ group, and .
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