Research Article

Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells

Figure 6

Schematic diagram of the mechanism by which MCL attenuates the inflammatory response of NRK-52E cells. MCL inhibits the activation of the NF-κB pathway and NLRP3 inflammasome by inhibiting the release of mROS, thereby ameliorating tubular inflammation.