The Change of Systemic Immune-Inflammation Index Independently Predicts Survival of Colorectal Cancer Patients after Curative Resection

Table 2

Clinicopathological variables of 206 colorectal cancer patients according to the ΔSII.

Variables	^†
	(35.9%)	(64.1%)
Age (years)
>60	38 (51.4)	35 (26.5)	<0.001
≤60	36 (48.6)	97 (73.5)
Gender
Male	33 (44.6)	75 (56.8)	0.092
Female	41 (55.4)	57 (43.2)
Smoking status
Yes	20 (27.0)	43 (32.6)	0.407
No	54 (73.0)	89 (67.4)
^†KPS
>80	51 (68.9)	97 (73.5)	0.485
≤80	23 (31.1)	35 (26.5)
Localization
Rectum	46 (62.2)	75 (56.8)	0.455
Colon	28 (37.8)	57 (43.2)
Surgical approach
Laparoscopy	42 (56.8)	75 (56.8)	0.993
Open	32 (43.2)	57 (43.2)
Adjuvant therapy
Yes	28 (37.8)	73 (35.4)	0.016
No	46 (62.2)	59 (64.6)
^†CEA (ng/ml)
>5	33 (44.6)	56 (42.4)	0.763
≤5	41 (55.4)	76 (57.6)
Pathological stage
Stages I-II	42 (56.8)	67 (50.8)	0.408
Stages III-IV	32 (43.2)	65 (49.2)
Differentiated degree
High-middle	61 (82.4)	112 (84.8)	0.650
Minor	13 (17.6)	20 (15.2)
Lymphatic invasion
Yes	32 (43.2)	67 (50.8)	0.300
No	42 (56.8)	65 (49.2)
Vascular invasion
Yes	27 (36.5)	72 (54.5)	0.013
No	47 (63.5)	60 (45.5)

^†KPS: ∆SII: the change in the systemic immune-inflammation index; KPS: Karnofsky Performance Status; CEA: carcinoembryonic antigen.