Role of Oxygen Supply in Macrophages in a Model of Simulated Orthodontic Tooth Movement

Figure 2

(a) Hif-1α gene expression under normoxic or hypoxic cell culture conditions with or without compressive force treatment. (b) Hif-1α gene expression on gas-impermeable or gas-permeable plates with or without pressure application. Reference genes: Eef1a1 and Sdha. (c) HIF-1α protein expression under normoxic or hypoxic cell culture conditions with or without compressive force treatment. Below: representative immunoblot. (d) HIF-1α protein expression on gas-impermeable or gas-permeable plates with or without pressure application. Below: representative immunoblot. Statistics: ANOVA followed by Holm Sidak’s or Tamhane’s T2 multiple comparison tests; AU = arbitrary units; ; ; .

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