Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice

<div>Serine deficiency exacerbated structure change of microbiota and decreased SCFA levels in D-galactose-treated mice. (a) Ratio of <i>Firmicutes</i>/<i>Bacteroidetes</i> in fecal microbiota; (b) proportion of <i>Clostridium XIVa</i>; (c) levels of short-chain fatty acids (SCFA) in feces; (d) relative mRNA expression of <i>Slc16a3</i>, <i>Slc16a7</i>, and <i>Gpr109a</i> in the brain. 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Mediators of Inflammation

fig2

Figure 2

Figure 2: Serine Deficiency Exacerbates Inflammation and Oxidative Stress via Microbiota-Gut-Brain Axis in D-Galactose-Induced Aging Mice 